Optimal use of SGLT2 inhibitors in diabetic kidney transplant recipients
نویسندگان
چکیده
Sodium-glucose cotransporter 2 inhibitor (SGLT2i), a glucosuric agent initially approved for use as an antidiabetic agent, was unexpectedly found to confer cardio-and reno-protective effects in individuals with or without type diabetes mellitus. Despite mounting evidence suggesting that SGLT2i provides cardio- and benefits both diabetic non-diabetic chronic kidney disease (CKD) patients the general population, reservations its transplant setting persist due concerns increased risk of genital mycotic urinary tract infections. A comprehensive review literature on efficacy safety recipients is herein presented followed by authors’ opinion optimal this patient population.
منابع مشابه
SGLT2 Inhibitors and the Diabetic Kidney.
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression. Sodium-glucose cotransporter 2 (SGLT2) inhibitors, the most recent glucose-lowering oral agents, may have the potential to exert nephroprotectio...
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ژورنال
عنوان ژورنال: Frontiers in nephrology
سال: 2022
ISSN: ['2813-0626']
DOI: https://doi.org/10.3389/fneph.2022.1014241